University of Texas Southwestern Medical Center

Why trials sponsored by University of Texas Southwestern Medical Center stopped, in this sample of ClinicalTrials.gov.

36 stopped trials with a clear reason; 94% ended for non-scientific reasons.

Trials

• EffCaMgCit to Prevent Mineral Metabolism and Renal Complications of Chronic PPI Therapy
  NCT05998863 · WITHDRAWN · logistics pi
  “No enrollment due to COVID”
• Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation
  NCT06273163 · TERMINATED · slow accrual
  “Funding ended, unable to reach recruitment goal.”
• Effect of a Childcare Resource on Cervical Cancer Prevention
  NCT06086054 · TERMINATED · logistics pi
  “Our previous childcare vendor's contract ended in January of 2025 and was not renewed. As of June 2025, a new vendor was still not established, and the decision was made by the study team to discontinue enrollment.”
• Non-operative vs. Operative Management of Acute Appendicitis in Vulnerable Patient Populations
  NCT05724628 · WITHDRAWN · regulatory
  “Project did not receive final IRB approvals. PI decided to withdrawn research study.”
• Liposomal Bupivacaine vs Standard Penile Block for Hypospadias Repair
  NCT04479371 · WITHDRAWN · funding business
  “Limited funding and resources to complete FDA requirements for enrollment”
• Mobile Intervention - Physical Activity in Cancer Treatment
  NCT03671304 · TERMINATED · funding business
  “The study was prematurely discontinued, the application utilized with the fitbit is no longer being supported.”
• The Effects of Low Dose Ketamine on Cardiovascular Function
  NCT04429685 · TERMINATED · funding business
  “The focus of the laboratory went a different direction given extramural funding”
• Hyperpolarized Carbon 13-Based Metabolic Imaging to Detect Radiation-Induced Cardiotoxicity
  NCT04044872 · TERMINATED · funding business
  “It has been terminated due to investigator decision to no longer pursue grant funding to support the study.”
• Diabetic Foot Ulcer and Wound Infection
  NCT03827902 · WITHDRAWN · slow accrual
  “Unable to recruit participants”
• Biological Effect of Warfarin on Pancreatic Cancer
  NCT03536208 · WITHDRAWN · slow accrual
  “no accrual for over 12 months”
• 7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events
  NCT04507373 · TERMINATED · funding business
  “No grant obtained. Enrolled participants were not assigned to the intervention and was study terminated”
• Sildenafil Treatment for Mild TBI
  NCT03598140 · TERMINATED · logistics pi
  “PI, Dr. Josh Gaston, left the institution and the study has been stopped.”
• SAbR Plus Ipilimumab Plus Nivolumab in Metastatic Melanoma Patients
  NCT03126461 · WITHDRAWN · slow accrual
  “the project was never initiated and no participants were enrolled, it was closed permanently”
• Study of Nintedanib and Chemotherapy for Advanced Pancreatic Cancer
  NCT02902484 · TERMINATED · slow accrual
  “The study was terminated due to futility and lack of future funding”
• Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery
  NCT03115151 · TERMINATED · slow accrual
  “The surgical team has difficulty to find level 1 and 2 fusions for the study.”
• Rapid Antidepressant Effects of Leucine
  NCT03079297 · TERMINATED · logistics pi
  “Covid-19”
• Ramelteon and Citicoline for Delirium
  NCT02840591 · WITHDRAWN · slow accrual
  “Stopped the study due to feasibility issues, no enrollment has taken place.”
• Effectiveness of Manual Therapy and Exercise in Shoulder OA
  NCT02587559 · WITHDRAWN · slow accrual
  “Could not recruit subjects as they routinely chose surgical option”
• LEE001 and Chemoembolization In Patients With Advanced Hepatocellular Carcinoma
  NCT02524119 · TERMINATED · funding business
  “This study was terminated after the sponsor withdrew our support”
• Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 Hyperlipoproteinemia
  NCT01675154 · TERMINATED · manufacturing supply
  “Due to unavailability of the drug.”
• IV Ibuprofen for the Prevention of Post-ERCP Pancreatitis
  NCT02241512 · TERMINATED · funding business
  “lack of funding”
• Ixabepilone and SBRT For Metastatic Breast Cancer
  NCT01818999 · WITHDRAWN · slow accrual
  “low accrual”
• Alternative Treatment Paradigm for Natalizumab Trial
  NCT01710228 · WITHDRAWN · funding business
  “sponsor stopped”
• Effect of Lower Extremity Ankle Foot Orthoses in Parkinson's Disease
  NCT01798927 · TERMINATED · other
  “Modifications are being made to protocol”
• Dilute Bleach Baths in Pediatric Patients With Atopic Dermatitis
  NCT01286220 · TERMINATED · slow accrual
  “the study was terminated due to participant drop out”
• Radiation Therapy and Ixabepilone in Treating Patients With High-Risk Stage III Prostate Cancer After Surgery
  NCT01079793 · WITHDRAWN · logistics pi
  “Overlapping study, PI preferred to enroll in alternate trial.”
• Pioglitazone as Second-Line in Patients With Metastatic Pancreatic Cancer After Treatment With Gemcitabine
  NCT00867126 · TERMINATED · slow accrual
  “low accrual”
• Transcranial Direct Current Stimulation (tDCS)-Enhanced Stroke Recovery
  NCT01007136 · TERMINATED · funding business
  “Funding limit reached due to slower then anticipated recruitment.”
• Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan
  NCT00840463 · TERMINATED · slow accrual
  “Poor enrolment”
• Study of N-Acetylcysteine in Acute Liver Failure (ALF)
  NCT00896025 · TERMINATED · funding business
  “This observational study was stopped after 140 patients were enrolled, no more funds available to continue.”
• RFT5-dgA Immunotoxin in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma
  NCT00667017 · TERMINATED · slow accrual
  “Slow accrual.”
• Use of TREM-1 Protein to Differentiate Viral and Bacterial Pneumonias in Intubated Children
  NCT00645619 · WITHDRAWN · logistics pi
  “PI is no longer with the University”
• Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma
  NCT00621036 · WITHDRAWN · futility
  “MyVax did not meet its primary endpoints”
• Time to Remission of Depressive Symptoms With Combined SSRI and Ramelteon
  NCT00642694 · TERMINATED · funding business
  “Enrollment discontinued based on mutually agreed upon decision by PI and funding sponsor”
• rTMS for Treatment of Depressed Phase of Bipolar Disorder Type II
  NCT00447096 · WITHDRAWN · logistics pi
  “No results, funding terminated and PI no longer at institution”
• Transplantation of Tissue Cultured Human Amniotic Epithelial Cells Onto Damaged Ocular Surfaces
  NCT00344708 · WITHDRAWN · slow accrual
  “Potential subjects did not meet eligibility criteria”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.