Johns Hopkins University

Why trials sponsored by Johns Hopkins University stopped, in this sample of ClinicalTrials.gov.

46 stopped trials with a clear reason; 93% ended for non-scientific reasons.

Trials

• Topical Tartrazine for Improved Skin Structure Visualization in Dermatology
  NCT06800183 · WITHDRAWN · logistics pi
  “The investigators are revisiting in vitro and in vivo studies to ensure the ability to replicate the results of the original paper before proceeding to the pilot clinical study.”
• Varying Bone Marrow-Derived Mesenchymal Stem Cells Concentrations' Impact on Rotator Cuff Repair Outcomes
  NCT06361797 · WITHDRAWN · logistics pi
  “PI leaving the institution”
• Impact of Exogenous Ketones on Sleep Disruption in Vulnerable Populations
  NCT06655649 · SUSPENDED · funding business
  “Funding changes, may resume later”
• Hearing Health for Korean American Older Adults With Mild Cognitive Impairment
  NCT06068933 · TERMINATED · slow accrual
  “This study is being terminated due to insufficient participant recruitment within the projected timeframe”
• Safety and Efficacy of IV Diazoxide as an Additive to Hyperkalemic Cardioplegia in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
  NCT04830982 · WITHDRAWN · regulatory
  “Withdrawn in IRB.”
• Brain-Computer Interface Implant for Severe Communication Disability
  NCT04576650 · WITHDRAWN · slow accrual
  “Investigational device no longer available. No subjects enrolled.”
• Opioid-free Total Hip Arthroplasty
  NCT04421196 · WITHDRAWN · regulatory
  “Currently does not have active IRB status.”
• Transplacental Aspirin Therapy for Early Onset Fetal Growth Restriction
  NCT04557475 · WITHDRAWN · other
  “We are modifying this trial's protocol and will resubmit a new application at a later date.”
• The Effects of Over-the-Counter Products on the Skin
  NCT03641430 · WITHDRAWN · other
  “The study design will need to be changed completely becasue of the change of research interest. We have decided to withdraw the study.”
• Connective Tissue Growth Factor in Patients With Neovascular Age Related Macular Degeneration
  NCT05038371 · TERMINATED · logistics pi
  “The study team decided to not publish a manuscript therefore we decided to terminate the study”
• Autoimmune Gastrointestinal Dysmotility: Symptoms, Pathogenesis and Treatment
  NCT04859829 · TERMINATED · logistics pi
  “PI moved to another institution and closed study.”
• Epidemiology and Treatment of Small-colony Variant Staphylococcus Aureus in Cystic Fibrosis
  NCT02547116 · WITHDRAWN · logistics pi
  “Administrative delay”
• Passport to Freedom: Health and Housing
  NCT04322903 · WITHDRAWN · logistics pi
  “Due to COVID 19 restrictions and protocol could not to be implemented safely for participants and researchers.”
• Safety, Efficacy, Longitudinal Costs and Patient-Centered Outcomes Using a TAAA Debranching Device
  NCT03637374 · TERMINATED · manufacturing supply
  “Investigational device is no longer manufactured”
• Keto-diet for Intubated Critical Care COVID-19
  NCT04358835 · WITHDRAWN · slow accrual
  “Study did not begin enrollment, multiple competing studies at same institution”
• Peginterferon Lambda-1a for the Prevention and Treatment of SARS-CoV-2 (COVID-19) Infection
  NCT04344600 · TERMINATED · slow accrual
  “Single center study with low enrollment”
• Fabrication of Sequential Naso-Alveolar Molding Appliances in the Treatment of Cleft Lip/Nose Deformities
  NCT04334590 · WITHDRAWN · slow accrual
  “no enrollment”
• Incline Positioning in COVID-19 Patients for Improvement in Oxygen Saturation
  NCT04344561 · TERMINATED · slow accrual
  “Inability to recruit”
• Augmented BLAdder NecK rEconstruction Trial for Improved Urinary Function After Radical Prostatectomy
  NCT04305379 · TERMINATED · logistics pi
  “Stopped due to COVID-19 pandemic, low priority among initiatives and officially terminated.”
• Feasibility and Efficacy of Dietary Interventions for Older Adults With Subjective Cognitive Decline
  NCT03585907 · WITHDRAWN · funding business
  “Lack of funding”
• Trabeculectomy Versus 2-iStent and Prostaglandin Study
  NCT03274323 · WITHDRAWN · regulatory
  “Difficulty obtaining IDE by the FDA. Currently not worthwhile to pursue further.”
• Trial of Orencia in Patients With Myasthenia Gravis
  NCT03059888 · TERMINATED · logistics pi
  “Mutual decision of sponsor and investigator due to logistical challenges”
• Contrast Enhanced Ultrasound Evaluation of Brain Perfusion in Neonatal Post-Hemorrhagic Hydrocephalus
  NCT03061045 · WITHDRAWN · logistics pi
  “PI is leaving the institution”
• Feasibility of Home Telehealth Monitoring for Improvement in Management of Hypertension for Secondary Stroke Prevention
  NCT03517709 · WITHDRAWN · slow accrual
  “No recruitment of subjects”
• Estradiol and Fear Extinction in Anorexia Nervosa (AN)
  NCT02792153 · WITHDRAWN · slow accrual
  “The study was withdrawn after 18 months due to lack of recruitment.”
• The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens
  NCT02998502 · TERMINATED · slow accrual
  “minimum subject accrual complete”
• Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders
  NCT02663206 · WITHDRAWN · slow accrual
  “Eligible candidate for recruitment was not found”
• Randomized, Split-body, Single-blinded Clinical Trial of NB-UVB Treatment for Vitiligo
  NCT02506101 · TERMINATED · slow accrual
  “Lack of enrollment and staff availability to administer treatment.”
• PReventing the EffectS of Intubation on DEglutition
  NCT02442102 · TERMINATED · slow accrual
  “slow recruitment”
• High-dose Cyclophosphamide for Severe Refractory Crohn Disease
  NCT01836289 · WITHDRAWN · slow accrual
  “Too difficult to recruit given new Crohn's medications approved”
• Functional Assessment of Coronary Artery Disease by CTA Flow Encoding
  NCT02286401 · TERMINATED · funding business
  “Recruitment lagged behind goal;exhaustion of funding.”
• Remote Ischemic Preconditioning to Prevent Contrast Nephropathy
  NCT02674451 · TERMINATED · slow accrual
  “poor enrollment”
• Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate Tissue Expander (TE) Reconstruction
  NCT02161705 · TERMINATED · slow accrual
  “Poor accrual due to change in standard of care procedure.”
• EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
  NCT02282111 · TERMINATED · other
  “Equality of results between the two groups at interim analysis”
• Androgen Regulation of Priapism in Sickle Cell Disease
  NCT01940718 · WITHDRAWN · funding business
  “Funding could not be secured”
• Microbiome of Urologic Chronic Pelvic Pain Syndrome
  NCT03027076 · WITHDRAWN · funding business
  “Funding for project not secured”
• Efficacy of High Flow Therapy in COPD At Home
  NCT02230020 · TERMINATED · funding business
  “Sponsor funding”
• Assessment of Penile Vibratory Stimulation Using the Viberect in Men With Mild-Moderate ED
  NCT01715571 · TERMINATED · slow accrual
  “Unable to obtain adequate recruitment”
• IL-10 Levels and Remote Ischemic Preconditioning in Acute Myocardial Infarction
  NCT01532206 · TERMINATED · funding business
  “Lack of funding”
• A Crohn's Disease Diet to Reduce Symptoms of Crohn's Disease
  NCT01897090 · WITHDRAWN · slow accrual
  “Unable to recruit”
• Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia
  NCT00721032 · WITHDRAWN · logistics pi
  “PI left the institution”
• The Effect of tDCS on Subcortical Brain Functioning
  NCT01602276 · TERMINATED · slow accrual
  “Difficulty identifying appropriate patients”
• Prospective Randomized Trial of Anterograde Single Balloon Versus Spirus Enteroscopy
  NCT01853241 · TERMINATED · manufacturing supply
  “SE system by Spirus Medical withdrawn from market in 2011”
• Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis
  NCT00728507 · TERMINATED · funding business
  “Funding withdrawn”
• Impact of Antibiotic Treatment on Prostate-Specific Antigen (PSA) Variability
  NCT00596453 · TERMINATED · slow accrual
  “Unable to recruit enough patients”
• The Effect of Pancreatic Polypeptide on Insulin Requirements for Type 1 & Post-pancreatectomy Diabetic Patients
  NCT00791076 · TERMINATED · logistics pi
  “PI left JHU”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.