Traumatic Brain Injury

Why trials studying Traumatic Brain Injury stopped, in this sample of ClinicalTrials.gov.

18 stopped trials with a clear reason; 94% ended for non-scientific reasons.

Trials

• Evaluation of the Abbott i-STAT TBI Biomarker Test
  NCT06766435 · TERMINATED · funding or business
  “Study was terminated early due to recruitment limitations and available funding for continued recruitment and follow up”
• Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity
  NCT04815967 · TERMINATED · funding or business
  “Company/sponsor business decision; not due to or related to any safety concerns”
• Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI)
  NCT04677829 · TERMINATED · funding or business
  “The study was terminated due to administrative, non-safety related reasons.”
• Hemp-Derived Botanical Dietary Supplementation During Recovery From Brain Injury
  NCT03826368 · WITHDRAWN · funding or business
  “Lack of initial funding after approval of study”
• Remote Ischemic Conditioning in Traumatic Brain Injury
  NCT03899532 · WITHDRAWN · slow enrollment
  “No eligible participants were enrolled.”
• Cerebrovascular Reactivity Assessed With fNIRS as a Biomarker of TCVI After Acute Traumatic Brain Injury in Military
  NCT04058132 · TERMINATED · funding or business
  “funding ran out after unanticipated length of time ( for IRB approval, CRADA, and start letter”
• fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population
  NCT03523507 · TERMINATED · staffing, sites or logistics
  “Study terminated due to COVID-19 restrictions”
• Assessing the Accuracy and the Impact of Standard-practice Ventricular Drainage on Intracranial Pressure Measurements Following Traumatic Brain Injury
  NCT02911675 · WITHDRAWN · regulatory or ethics
  “Due to the lack of approval from the Air Force IRB patient enrollment was never initiated. Thus, no clinical results could be examined or can be reported”
• Fresh Intravenous Blood Samples for TBI Diagnostic Assay Development With Philips Point of Care System
  NCT03060109 · TERMINATED · funding or business
  “Diagnostic platform no longer under development; study termination not related to any safety issues”
• TBI MR Study 3 Houston Methodist
  NCT02218216 · TERMINATED · funding or business
  “Sponsor terminated study early to start a larger feasability study”
• Advanced MRI Applications for Mild Traumatic Brain Injury
  NCT02070588 · TERMINATED · funding or business
  “Sponsor terminated early as moving to a new larger study program”
• The Role of Cerebral Oximetry in Pediatric Concussion Assessment
  NCT02036333 · TERMINATED · staffing, sites or logistics
  “Key Personnel Left Institution Prior to Study Completion”
• The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery
  NCT01606111 · TERMINATED · slow enrollment
  “Poor patient recruitment”
• Feasibility of the Radio-Frequency Microstimulator System to Improve Arm Function Following Traumatic Brain Injury
  NCT01488981 · TERMINATED · slow enrollment
  “low enrollment”
• Hyperbaric Oxygen Therapy in Chronic Traumatic Brain Injury or Post-Traumatic Stress Disorder
  NCT01105962 · TERMINATED · funding or business
  “new regulatory requirements will require funding for restart as a new study”
• Study to Evaluate the Efficacy and Safety of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury
  NCT00893789 · TERMINATED · funding or business
  “Study has been stopped by sponsor decision.”
• Effects of Hypothermia Upon Outcomes After Acute Traumatic Brain Injury
  NCT00178711 · TERMINATED · futility
  “Futility”
• Study of Oxycyte in Severe Closed Head Injury
  NCT00174980 · TERMINATED · slow enrollment
  “Low enrollment”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.