Parkinson Disease

Why trials studying Parkinson Disease stopped, in this sample of ClinicalTrials.gov.

33 stopped trials with a clear reason; 91% ended for non-scientific reasons.

Trials

• Effects of Blood Pressure on Cognition and Cerebral Hemodynamics in PD
  NCT06252376 · WITHDRAWN · funding business
  “Never started; study did not receive funding”
• A Phase 1b Study of the NLRP3 Inhibitor VENT-02 in Patients With Mild to Moderate Parkinson's Disease
  NCT06822517 · TERMINATED · funding business
  “Sponsor decision”
• Observational Small Intestine and Blood Fingerprint (SmIle) Study in Parkinson's Disease
  NCT06003608 · TERMINATED · slow accrual
  “Study recruitment phase exceeded the time allotted”
• Transcutaneous Vibro-Acoustic Therapy in Parkinson Disease
  NCT05962476 · TERMINATED · funding business
  “Study discontinued due to a lack of resources.”
• Altropane Dose for Imaging Patients With Suspected Parkinson's Disease
  NCT05636852 · TERMINATED · funding business
  “Business Decision”
• Brain Small Chain Fatty Acid Metabolism in Parkinson Disease: Tributyrin Supplementation
  NCT05446168 · TERMINATED · funding business
  “Withdrawal of funding”
• Feasibility of Remote Measures and Assessments in Deep Brain Stimulation for Parkinson's Disease (FoRMA-DBS)
  NCT05219019 · WITHDRAWN · slow accrual
  “Insufficient interest by potential participants.”
• Robotic Gait Rehabilitation in Parkinson's Disease
  NCT05218187 · TERMINATED · logistics pi
  “The PI was no longer able to successfully recruit participants and funding was depleted.”
• Effect of Meditation and Controls and Subjects With Parkinson's Disease on Brain Activity Measured by fMRI With FDOPA
  NCT05103618 · WITHDRAWN · funding business
  “funding not obtained”
• Manipulating and Optimizing Brain Rhythms for Enhancement of Sleep
  NCT05089682 · TERMINATED · logistics pi
  “Unable to enroll subjects due to COVID and complexity of study.”
• The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson's Disease
  NCT04346394 · WITHDRAWN · logistics pi
  “COVID-19”
• Study in Parkinson's Disease Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components
  NCT04377945 · TERMINATED · funding business
  “Business reasons”
• Efficacy and Safety or Rhythmic Auditory Stimulation (RAS) for Gait and Balance Disorders in Parkinson's Disease
  NCT03278639 · WITHDRAWN · funding business
  “We could not fund the study”
• PK Study in Patients With Parkinson's Disease With IZD174
  NCT04338997 · WITHDRAWN · funding business
  “Strategic decision by Sponsor”
• A Pilot Study to Explore the Role of Gut Flora in Parkinson's Disease
  NCT04148326 · WITHDRAWN · funding business
  “Company focus shifted”
• Aquatic Group Exercise for People With Parkinson Disease
  NCT04291027 · TERMINATED · logistics pi
  “The study needed to be stopped due to the COVID-19 pandemic.”
• Oral Therapeutic Education in Stimulated Parkinsonian Patients
  NCT03965390 · TERMINATED · logistics pi
  “impossibility of continuing the study due to lack of medical staff”
• Molecular and Functional Imaging in SNCA, Parkin and PINK1
  NCT04084509 · WITHDRAWN · logistics pi
  “Change of circumstances for CI/PI.”
• A Study to Assess the Safety and Effectiveness of Pridopidine Compared to Placebo in the Treatment of Levodopa-Induced Dyskinesia in Patients With Parkinson's Disease
  NCT03922711 · TERMINATED · logistics pi
  “COVID-19”
• Vibrational Therapy to Improve Gait and Balance in Parkinson's Disease
  NCT03872115 · WITHDRAWN · other
  “Device feasibility study, not clinical trial”
• Evaluation of Using Vibrotactile Coordinated Reset for Management of Parkinson's Disease
  NCT03857867 · TERMINATED · logistics pi
  “Covid 19”
• Treatment of Balance Disorders in Parkinson's Patients Using SpotOn Balance Glasses
  NCT03942172 · SUSPENDED · other
  “The study protocol needed to be modified”
• SMARTfit Training for Parkinson's Disease
  NCT03921359 · TERMINATED · logistics pi
  “In compliance with research restrictions imposed due to the COVID-19 pandemic.”
• Clinical Characteristics of Parkinson's Disease Subjects With Severe Hypertension During Motor OFFs.
  NCT03433950 · SUSPENDED · logistics pi
  “COVID-19 Research Restrictions”
• Handwriting Interventions for People With Parkinson's
  NCT03369587 · TERMINATED · logistics pi
  “Not feasible to restarted after Covid pandemic - analysis will be on data collected before study suspended”
• Videofluoroscopic Swallowing Study (VFSS)
  NCT03387267 · TERMINATED · futility
  “Study terminated due to futility”
• Relative Bioavailability Study of Ropinirole Implants in Parkinson's Patients on L-Dopa Switched From Oral Ropinirole
  NCT03250117 · TERMINATED · funding business
  “This study was terminated for reasons not related to efficacy or safety”
• Safety and Efficacy of Adaptive DBS Vs Conventional DBS in Patients With Parkinson's Disease
  NCT03422757 · TERMINATED · funding business
  “Company strategic decision”
• Validation and Standardization of a Battery Evaluation of the Socio-emotional Functions in Various Neurological Pathologies
  NCT03052712 · TERMINATED · slow accrual
  “not enough patients”
• Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
  NCT02897063 · TERMINATED · slow accrual
  “enrollment goal was not met.”
• Establishment of a Human Tissue Bank for Studying the Microbial Etiology of Neurodegenerative Diseases
  NCT01954875 · WITHDRAWN · funding business
  “Study no longer funded”
• The Use of Sensory or Motor Cues Using Electrical Stimulation to Reduce Gait Freezing in Patients With Parkinson Disease
  NCT00762814 · TERMINATED · funding business
  “There was no funding for the device to be used in the study.”
• Perioperative Treatment of Parkinsonian Patients With Parenteral Amantadine
  NCT00600093 · TERMINATED · logistics pi
  “PI leaving the institute for a fellowship.”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.