Lung Cancer

Why trials studying Lung Cancer stopped, in this sample of ClinicalTrials.gov.

51 stopped trials with a clear reason; 86% ended for non-scientific reasons.

Trials

• Exploratory Study of Inhaled Afatinib Dimaleate PK Profile
  NCT06897735 · TERMINATED · other
  “adjustment of the study design taking into account the receipt of primary data”
• Adjunctive Intravenous Ascorbic Acid for Advanced Non-Small Cell Lung Cancer
  NCT05849129 · TERMINATED · slow accrual
  “Insufficient recruitment”
• A Study to Test Different Doses of BI 765049 Alone and in Combination With Ezabenlimab in Asian People With Advanced Cancer (Solid Tumours) Positive for B7-H6
  NCT06091930 · TERMINATED · funding business
  “Sponsor decision”
• Lorlatinib in Combination With Chemotherapy in Participants With Metastatic Anaplastic Lymphoma Kinase Positive (ALK+) Non-small Cell Lung Cancer (NSCLC) Who Progressed on Single-agent Lorlatinib
  NCT05948462 · WITHDRAWN · funding business
  “Study withdrawn by pharmaceutical funding partner”
• Study of LUNG Stereotactic Adaptive Ablative Radiotherapy
  NCT04917224 · WITHDRAWN · funding business
  “ViewRay (funding agency) has filed under Chapter 11, U.S. Bankruptcy Code. ViewRay's clinical research support is paused and studies will not be paid directly by ViewRay. As such, the sponsor has closed the study without enrolling participants.”
• Charcoal in Lung Cancer Patients Undergoing TEMLA
  NCT04928950 · WITHDRAWN · logistics pi
  “Because of logistic challenges and lack of product among other factors, we decided to completely withdrawn this study.”
• Breath Analysis in Early Stage Lung Cancer Using Infrared Spectroscopy
  NCT04556435 · TERMINATED · funding business
  “Change in the sponsor's business strategy (new focus on breast cancer)”
• LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
  NCT04027946 · TERMINATED · slow accrual
  “Study was terminated due to slow accrual.”
• A Study of Nivolumab and Intrapleural Talimogene Laherparepvec for Malignant Pleural Effusion
  NCT03597009 · TERMINATED · slow accrual
  “due to slow accrual and withdrawal of funding”
• Study of Nivolumab in Combination With GM.CD40L Vaccine in Adenocarcinoma of the Lung
  NCT02466568 · WITHDRAWN · funding business
  “Funding unavailable”
• Circulating Tumor DNA in Patients at High Risk for Lung Cancer
  NCT02715102 · TERMINATED · slow accrual
  “Patient accrual was slow due to exclusion of patients with prior cancers”
• Advanced Non-Small Cell Lung Cancer Progressing After at Least One Prior Therapy For Metastatic Disease
  NCT02469701 · TERMINATED · slow accrual
  “Lack of accrual”
• NEoadjuvant Gefitinib fOllowed by Surgery and gefiTinib In unresectAble sTage III NSCLC With EGFR Mutations.
  NCT02347839 · WITHDRAWN · slow accrual
  “Slow accrual”
• Medicoeconomic Evaluation of Two Surgical Techniques for Lobectomy in the Lung Cancer
  NCT02502318 · TERMINATED · slow accrual
  “lack of inclusions”
• Measuring the Effect of Radiation Therapy on Patient Activity Levels
  NCT02694380 · TERMINATED · slow accrual
  “Low accrual”
• Registry Measuring Impact of RNA Expression Testing on Treatment Decisions in Early Stage Lung Cancer and Assessing the Disease-free Survival With Long-term Follow-up (ONC006)
  NCT02121899 · TERMINATED · funding business
  “company decision to terminate”
• Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy
  NCT02115464 · TERMINATED · slow accrual
  “The accrual rate was not high enough to reach the target sample size.”
• A Pilot/Phase II Study of Gamma Knife Radiosurgery for Brain Metastases Using 3Tesla MRI and Rational Dose Selection
  NCT02005614 · TERMINATED · slow accrual
  “Unable to recruit patients.”
• A Protocol of Irinotecan for Carcinoma of the Lung
  NCT01654081 · WITHDRAWN · slow accrual
  “Slow accrual”
• A Dose Ascending Study of Gemcitabine Elaidate (CO-101) in Combination With Cisplatin
  NCT01641575 · TERMINATED · futility
  “Registrational study did not meet endpoint so entire program (including CO-101-011) was terminated.”
• CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer
  NCT01583686 · TERMINATED · slow accrual
  “Study terminated due to slow/insufficient accrual.”
• Perioperative Rehabilitation in Operation for Lung Cancer
  NCT01893580 · TERMINATED · slow accrual
  “Due to low recruiment rate, the study design is chanced to a feasibility study”
• A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients With Prostate, Colorectal, Lung and Pancreatic Cancer
  NCT01940237 · TERMINATED · slow accrual
  “Low recruitment”
• Feasibility Study to Estimate Number of Patients With Precancerous Areas in Their Airways and the Response to Gefitinib
  NCT01405846 · TERMINATED · futility
  “Futility”
• Chest Computed Tomography (CT) Screening Study With Antibody Testing
  NCT01203579 · WITHDRAWN · funding business
  “Due to lack of funding”
• Methylprednisolone Before Fludeoxyglucose-Labeled Positron Emission Tomography in Patients With Lung Cancer
  NCT01789892 · WITHDRAWN · slow accrual
  “no patient accrual”
• 4D-CT-based Ventilation Imaging for Adaptive Functional Guidance in Radiotherapy
  NCT01034514 · TERMINATED · funding business
  “business decision”
• Surgical Versus Non-surgical Staging of Lung Cancer
  NCT01117714 · TERMINATED · slow accrual
  “Accrual was poor at two other sites and manuscript was published which describing another study which accomplished the goals of this project.”
• Internet-Based Clinical Information and Blood Sample Collection From Patients With Non-Small Cell Lung Cancer Who Never Smoked Cigarettes
  NCT01141218 · TERMINATED · slow accrual
  “slow accrual”
• Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
  NCT00892801 · TERMINATED · slow accrual
  “Terminated due to low accrual. Study was closed to accrual prematurely and did not continue on to Phase II.”
• CryoSpray Ablation(tm)Thoracic Patient Registry
  NCT00785239 · WITHDRAWN · funding business
  “Business Reasons”
• Dasatinib in Advanced Non-small Cell Lung Cancer (NSCL) With Ex Vivo and In Vivo Assessment of Tumor Target Modulation
  NCT00858403 · TERMINATED · slow accrual
  “Slow Accrual”
• Vaccine Therapy in Patients With Stages IIIB/IV Non-Small Cell Lung Cancer Who Have Finished First-Line Chemotherapy
  NCT00534209 · TERMINATED · logistics pi
  “Per request of Principal Investigator this study was closed.”
• S0716 Vandetanib and Docetaxel in Treating Patients With Advanced Solid Tumors
  NCT00937417 · WITHDRAWN · other
  “Withdrawn because SWOG no longer pursuing this study at this time”
• Zoledronic Acid and Positron Emission Tomography in Treating Patients With Advanced Non-Small Cell Lung Cancer
  NCT00559897 · TERMINATED · slow accrual
  “Slow accrual”
• Flaxseed Supplement in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Undergoing Chemotherapy and Radiation Therapy
  NCT00955942 · TERMINATED · slow accrual
  “Insufficient enrollment”
• Thermal Signature of Patients Undergoing Radiation Therapy
  NCT00508313 · WITHDRAWN · slow accrual
  “Study closed early without enrollment.”
• Pilot Study of (61)CuATSM-PET Imaging in Cancer Patients
  NCT00585117 · TERMINATED · funding business
  “change in imaging priorities”
• Phase I/II Trial of RAD001 Plus Docetaxel in Patients With Metastatic or Recurrent Non-Small Cell Lung Cancer
  NCT00406276 · TERMINATED · futility
  “data analysis showed insufficient drug efficacy”
• Phase I-II for Patients With Recurrent or Refractory Non-small Cell Lung Cancer (NSCLC)
  NCT00411593 · WITHDRAWN · slow accrual
  “Lack of Patient Accrual”
• Pemetrexed Disodium and Cisplatin Before or After Surgery in Treating Patients With Stage IB or Stage II Non-Small Cell Lung Cancer That Can be Removed by Surgery
  NCT00389688 · TERMINATED · slow accrual
  “low accrual”
• Study of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based Chemotherapy
  NCT00290017 · TERMINATED · regulatory
  “FDA Hold May 2007”
• Pharmacokinetic & Pharmacodynamic Study of ABT-751 With Carboplatin in Patients With Advanced Lung Cancer
  NCT00735878 · TERMINATED · futility
  “data from a similar did not show efficacy.”
• Satraplatin for Locally Advanced Non-Small Cell Lung Cancer With Simultaneous Radiotherapy
  NCT00093132 · TERMINATED · funding business
  “Sponsor decided to discontinue study drug development.”
• Docetaxel and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
  NCT00118131 · TERMINATED · slow accrual
  “Slow accrual”
• High-Dose 3-Dimensional Conformal Radiation Therapy in Treating Patients With Inoperable Stage I, Stage II, or Stage IIIA Non-Small Cell Lung Cancer
  NCT00062335 · TERMINATED · slow accrual
  “low accrual”
• Surveillance For New Lung Primaries
  NCT00205439 · TERMINATED · slow accrual
  “low accrual”
• Radiation Therapy in Preventing Brain Metastases in Patients With Small Cell Lung Cancer
  NCT00006344 · WITHDRAWN · logistics pi
  “PI left institution”
• Carboplatin, Paclitaxel, and Radiation Therapy With or Without Thalidomide in Patients With Stage III Non-small Cell Lung Cancer
  NCT00004859 · TERMINATED · futility
  “Trial was stopped early for futility”
• Surgery, Gemcitabine, Cisplatin, and Radiation Therapy in Treating Patients With Stage II or Stage III Non-Small Cell Lung Cancer
  NCT00530634 · TERMINATED · slow accrual
  “Poor accrual”
• Chemotherapy Plus Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer That Cannot Be Surgically Removed
  NCT00003803 · TERMINATED · slow accrual
  “low accrual”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.