Hepatitis C

Why trials studying Hepatitis C stopped, in this sample of ClinicalTrials.gov.

21 stopped trials with a clear reason; 95% ended for non-scientific reasons.

Trials

• HCV Test and Treat Utilizing Simplified HCV Patient Education
  NCT05582681 · TERMINATED · funding or business
  “The funding was halted.”
• Utilization of MAsS in Patients Undergoing LT for HCC
  NCT05184283 · TERMINATED · funding or business
  “Discontinued by Amra Medical due to funding.”
• Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Kidney Transplant
  NCT03623568 · WITHDRAWN · regulatory or ethics
  “did not move forward with IRB approval, competing study”
• Early Post-marketing Study of Daclatasvir (Daklinza®) + Asunaprevir (Sunvepra®) in the Treatment of Chronic Hepatitis C (CHC) in Adults
  NCT03208322 · WITHDRAWN · funding or business
  “There was a change in the strategy to complete the RMP with HA.”
• A Single-arm Evaluation of the Effect of HCV Treatment on Cardiovascular Disease Risk
  NCT03585101 · WITHDRAWN · funding or business
  “Funding no longer available”
• Registry-based HCV Care Cascade Navigation at Atlanta's Grady Memorial Hospital
  NCT03441542 · TERMINATED · slow enrollment
  “Insufficient enrollment. Reasons for low enrollment were low eligibility, and difficulty contacting patients.”
• Evaluation of Daclatasvir (DCV) in Combination With Sofosbuvir (SOF) in Children With Chronic Hepatitis C (CHC) Infection
  NCT03487848 · TERMINATED · funding or business
  “Business objectives have changed”
• DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant
  NCT03208127 · TERMINATED · funding or business
  “Protocol transitioned to standard of care, no funding available to continue support of research work or data analysis”
• Impact of Hepatitis C Therapy and Bone Health
  NCT03221582 · TERMINATED · slow enrollment
  “Site unable to recruit the agreed upon number of participants”
• A Long Term Follow-up Study in Participants Treated in a Preceding Phase 2 or 3 Study With a Regimen Containing Odalasvir and AL-335 With or Without Simeprevir for the Treatment of Hepatitis C Virus (HCV) Infection
  NCT03099135 · TERMINATED · funding or business
  “Recruitment prematurely stopped based on decision to stop HPC program (not due to safety or efficacy results) + On 31 Jan 2018 decision to stop the study”
• Efficacy and Safety of Uprifosbuvir (MK-3682) + Ruzasvir (MK-8408) in Treating Hepatitis C Virus Infection Genotypes 1-6 (MK-3682-041)
  NCT02956629 · TERMINATED · funding or business
  “The study was terminated based on review of Phase 2 efficacy data”
• Improving Fibrosis Outcomes With Metformin
  NCT02306070 · WITHDRAWN · funding or business
  “insufficient funding”
• C Tracker, Hepatitis C, Care & Collaboration - Patient Reported Outcomes Survey Study
  NCT02568540 · TERMINATED · slow enrollment
  “Lack of enrollment”
• Effect of Harvoni on Proteinuria and eGFR in Hepatitis C Virus Associated Chronic Kidney Disease (CKD)
  NCT02503735 · TERMINATED · slow enrollment
  “Unable to meet enrollment goal”
• Long-Term Follow-Up Safety Monitoring of Patients Dosed in the First-in-Man Phase I/II Study of TT-034.
  NCT02315638 · TERMINATED · safety
  “Long term safety follow-up no longer required”
• Technology-Based Application To Improve The Triple Therapy Adherence Rate In Subjects With Hepatitis C Infection
  NCT02070107 · WITHDRAWN · funding or business
  “Sponsored withdrew”
• Telaprevir, Peg-IFN-alfa-2a, and RBV in Treatment-Experienced Black/African American and Non-Black/African American Subjects With Genotype 1 Chronic Hepatitis C
  NCT01467492 · TERMINATED · funding or business
  “It was decided by Sponsor on 13 January 2014 to terminate study early at primary efficacy endpoint as part of a decision to modify drug development plan.”
• Peginterferon and Ribavirin, With or Without Telaprevir, for Genotype 1 Hepatitis C and IL28B CC Polymorphism
  NCT01415141 · WITHDRAWN · funding or business
  “Lack of funding”
• Study of Maternal Hepatitis C Infection and Influenza Vaccination in Pregnancy
  NCT00810875 · TERMINATED · slow enrollment
  “Terminated due to lack of enrollment”
• Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients
  NCT00655226 · TERMINATED · slow enrollment
  “low enrollment”
• BreathID Multi-center HCV Liver Breath Test Study
  NCT00350714 · TERMINATED · regulatory or ethics
  “Due to FDA comments, protocol changed; new trial will be proposed shortly”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.