Cystic Fibrosis

Why trials studying Cystic Fibrosis stopped, in this sample of ClinicalTrials.gov.

24 stopped trials with a clear reason; 96% ended for non-scientific reasons.

Trials

• A Study to Test How Well BI 3720931 is Tolerated and Whether it Improves Lung Function in People With Cystic Fibrosis (Lenticlair™ 1)
  NCT06515002 · TERMINATED · funding business
  “Sponsor decision”
• Symptom Based Performance of Airway Clearance After Starting Highly Effective Modulators for Cystic Fibrosis (SPACE-CF)
  NCT05392855 · TERMINATED · slow accrual
  “Low recruitment, low interest from participant population”
• Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fibrosis
  NCT05561764 · TERMINATED · slow accrual
  “Difficulty enrolling”
• Thermic Effect of Feeding in Cystic Fibrosis
  NCT03931252 · WITHDRAWN · slow accrual
  “Unable to recruit participants”
• Epidemiology and Treatment of Small-colony Variant Staphylococcus Aureus in Cystic Fibrosis
  NCT02547116 · WITHDRAWN · logistics pi
  “Administrative delay”
• Measuring and Improving Coproduction Using coopeRATE
  NCT04060329 · TERMINATED · logistics pi
  “Reasons associated with COVID-19 pandemic led to cancellation of Phase 2”
• A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat® Inhaler - BALANCE - CF™1
  NCT04059094 · TERMINATED · funding business
  “Not due to safety reasons”
• Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance
  NCT05267418 · TERMINATED · logistics pi
  “COVID19 pandemia”
• Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)
  NCT02323100 · TERMINATED · funding business
  “funding ended”
• Study of Aztreonam for Inhalation in Children With Cystic Fibrosis and New Infection of the Airways by Pseudomonas Aeruginosa Bacteria
  NCT03219164 · TERMINATED · logistics pi
  “Study was terminated early by sponsor due to the challenges and risks introduced by Coronavirus disease 2019 (COVID-19) pandemic.”
• Effect of Acid Blockade on Microbiota and Inflammation in Cystic Fibrosis (CF)
  NCT02769637 · TERMINATED · slow accrual
  “unable to meet the target enrollment goal”
• Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease
  NCT02950116 · TERMINATED · logistics pi
  “Availabe time for inclusion ended (master thesis)”
• Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students
  NCT03041571 · WITHDRAWN · logistics pi
  “PI is no longer with UF. No New PI assigned to date.”
• Efficacy and Safety of Inhaled Nitric Oxide (NO) in Cystic Fibrosis (CF) Patients
  NCT02498535 · TERMINATED · logistics pi
  “Terminated for the safety of cystic fibrosis clinical trial subjects due to Covid-19.”
• Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations
  NCT02971839 · TERMINATED · funding business
  “Decision by Sponsor.”
• A Study to Evaluate Efficacy and Safety of Ivacaftor in Subjects With Cystic Fibrosis Aged 3 Through 5 Years Who Have a Specified CFTR Gating Mutation
  NCT02742519 · TERMINATED · slow accrual
  “Low enrollment.”
• Impact of Availability of Showerpatch for Patients With Intravenous Catheters
  NCT02324868 · TERMINATED · logistics pi
  “logistic problems”
• Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively
  NCT02605538 · WITHDRAWN · logistics pi
  “Time and resource deficiency at the Stockholm CF Center.”
• Zoledronic Acid in Cystic Fibrosis
  NCT01702415 · WITHDRAWN · funding business
  “Lack of funding”
• High Flow Nasal Oxygen for Children With Cystic Fibrosis Presenting With Respiratory Failure - a Randomized Controlled Study
  NCT01810536 · TERMINATED · slow accrual
  “It was impossible for us to include patients”
• Sitagliptin in Cystic Fibrosis-Related Diabetes
  NCT01257464 · TERMINATED · slow accrual
  “Lack of recruitment”
• A Trial of Pulmozyme Withdrawal on Exercise Tolerance in Cystic Fibrosis Subjects With Severe Lung Disease (TOPIC)
  NCT00434278 · TERMINATED · logistics pi
  “This study was terminated for administrative reasons. There were no safety concerns.”
• Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Subjects
  NCT00125346 · TERMINATED · other
  “per Data Monitoring Committee recommendation”
• Effect of Non-Invasive Ventilation in Cystic Fibrosis Patient With Chronic Respiratory Failure.
  NCT00208078 · TERMINATED · slow accrual
  “Not enough patient recruited”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.