Coronary Artery Disease

Why trials studying Coronary Artery Disease stopped, in this sample of ClinicalTrials.gov.

41 stopped trials with a clear reason; 95% ended for non-scientific reasons.

Trials

• 3rd Generation Resorbable Magnesium Scaffolds vs Biodegradable Polymer Stents in NSTE/ACS
  NCT06409117 · WITHDRAWN · funding business
  “No funding”
• Senescence in Myocardial Infarction
  NCT07693712 · TERMINATED · funding business
  “Staffing challenges and subsequent withdrawal of funding.”
• CSI Percutaneous Ventricular Assist Device (pVAD) Second in Human Study
  NCT05695716 · WITHDRAWN · funding business
  “No subjects enrolled; termination was business decision after acquisition of CSI by Abbott.”
• The Effect of Continued Mechanical Ventilation on the Occurrence of Myocardial Ischemia
  NCT05417217 · TERMINATED · logistics pi
  “After the passing of the principal investigator, the clinical trial could not be continued.”
• Notify 2: An Evaluation of the Impact of Notification of Incidental Coronary Artery Calcium on Statin Rates
  NCT05394181 · WITHDRAWN · funding business
  “Change in resource allocation”
• Assessing Diagnostic Value of Non-invasive FFR-CT in Coronary Care in the Emergency Department
  NCT05325112 · TERMINATED · funding business
  “Sponsor decision to terminate the study”
• Double Rewire Versus Double Kissing Crush Stenting Technique in Left Main Bifurcation Lesions
  NCT05258318 · WITHDRAWN · slow accrual
  “Low recruitment rate”
• A Zero Acute Kidney Injury Strategy for Percutaneous Coronary Intervention in Patients With ChronicKidney Disease
  NCT04928092 · WITHDRAWN · logistics pi
  “The PI is leaving the institution”
• Effect of Remote Intervention in Patients With SCAD
  NCT04795492 · WITHDRAWN · slow accrual
  “Unable to recruit enough patients”
• Causes of Health Disparities in African Americans With Coronary Artery Disease on Clopidogrel
  NCT04619381 · WITHDRAWN · funding business
  “The study funding was dropped with no patients enrolled”
• Registry Study to Evaluate the Performance and Safety of Roxwood Medical Catheters in Arteries of Participants With a Stenotic Lesion or Chronic Total Occlusion (CTO)
  NCT04059536 · WITHDRAWN · funding business
  “Sponsor decision”
• Cardiac Cath Lab Staff Radiation Exposure
  NCT03959072 · TERMINATED · slow accrual
  “Sponsor decision due to lower than anticipated enrollment”
• The MyoVista Angiography Angioplasty Percutaneous Coronary Intervention Trial
  NCT03635801 · TERMINATED · logistics pi
  “Due to PI's unavailability”
• Bioresorbable Vascular Scaffolds Versus Stents in Patients With Chronic Total Occlusion
  NCT02739685 · TERMINATED · slow accrual
  “Slow enrollment, access to devices”
• Simultaneous Assessment of FFR and SPECT
  NCT02749045 · TERMINATED · slow accrual
  “Slow recruitment, funding period ended”
• IRIS-BVS AMI Registry
  NCT02699671 · TERMINATED · safety
  “current BVS safety issue”
• Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease
  NCT02454426 · WITHDRAWN · logistics pi
  “PI left institution”
• Feasibility and Diagnostic Accuracy of Myocardial SPECT Using Early Imaging Protocol
  NCT02136706 · WITHDRAWN · logistics pi
  “Sponsor and site were unable to complete a final contract to support the study”
• Ferumoxytol-enhanced Magnetic Resonance Imaging
  NCT06348524 · TERMINATED · regulatory
  “new IRB not available”
• Functional Assessment of Coronary Artery Disease by CTA Flow Encoding
  NCT02286401 · TERMINATED · funding business
  “Recruitment lagged behind goal;exhaustion of funding.”
• Telerobotic Ultrasound for Carotid Imaging - Feasibility Study
  NCT05654935 · WITHDRAWN · logistics pi
  “Failure to procure funding and technical logistics”
• Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study
  NCT01916902 · WITHDRAWN · slow accrual
  “Despite a large number of patients screened, very few met eligibility guidelines.”
• A Study To Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI
  NCT01848106 · TERMINATED · regulatory
  “Clinical Hold”
• Deutsches Dual Therapy Stent Register
  NCT02102997 · TERMINATED · slow accrual
  “Low enrolment”
• Graft Patency Analysis of the Right Coronary Artery System
  NCT01559350 · TERMINATED · slow accrual
  “Poor recruiting rate”
• ABSORB PHYSIOLOGY Clinical Investigation
  NCT01308346 · TERMINATED · slow accrual
  “Due to a challenging protocol inclusion/ exclusion criteria, only one subject was enrolled since the trial was initiated in June 2011.”
• Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations
  NCT01262625 · TERMINATED · funding business
  “Funding timeline completed”
• Vitamin D and T-Regulatory Cells in Coronary Artery Disease
  NCT01183962 · TERMINATED · slow accrual
  “slow enrollment, funding ended”
• Optical Coherence Tomography Evaluation of a Biodegradable Polymer-based Drug-eluting Stent
  NCT01060306 · WITHDRAWN · funding business
  “Funding issues”
• Relationship Between Initial Plaque Characteristics and Stent Surface Coverage Patterns
  NCT01024179 · TERMINATED · slow accrual
  “Difficulty in enrolling the required number of participants has made it impractical to proceed with the trial.”
• Stereotaxis Computed Tomography (CT) Co-Registration Study
  NCT00994331 · TERMINATED · slow accrual
  “Study terminated due to lack of enrollment.”
• Alternative in Beta Blocker Intolerance: The ABBI Trial
  NCT00893984 · TERMINATED · slow accrual
  “Lack of patient recruitment”
• SPIRIT Small Vessel Registry
  NCT00783796 · TERMINATED · funding business
  “Study stopped at 3 years. Funding for trial withdrawn by sponsor.”
• Bypass Surgery Versus Everolimus-Eluting Stent Implantation for Multivessel Coronary Artery Disease (BEST)
  NCT00997828 · TERMINATED · slow accrual
  “Problem with recruitment of subjects”
• PET/CT Study in the Diagnosis of Coronary Plaque
  NCT00850473 · TERMINATED · logistics pi
  “Sub-investigator left the university”
• French Post-Marketing Surveillance Survey
  NCT00855478 · TERMINATED · funding business
  “Early termination of patient enrollment based on business decision”
• Cell Therapy in Chronic Ischemic Heart Disease
  NCT00362388 · TERMINATED · slow accrual
  “low enrollling”
• Stem Cell Study for Patients With Heart Disease
  NCT00221182 · TERMINATED · slow accrual
  “slow recruitment of the study subjects”
• Both Exercise and Adenosine Stress Testing
  NCT00200629 · TERMINATED · slow accrual
  “Poor enrollment”
• Tissue-Type Plasminogen Activator (t-PA) Release Predicts Major Adverse Cardiac Events (MACE) in Patients With Non-critical Coronary Artery Disease
  NCT00868855 · TERMINATED · slow accrual
  “poor enrollment”
• Full-dose Atorvastatin After Acute Coronary Syndrome (ACS) in Non-revascularisable Coronary Artery Disease
  NCT01187992 · TERMINATED · futility
  “Interim analysis showed significant effect in favour of full-dose atorvastatin.”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.