Cardiovascular Diseases

Why trials studying Cardiovascular Diseases stopped, in this sample of ClinicalTrials.gov.

26 stopped trials with a clear reason; 77% ended for non-scientific reasons.

Trials

• Senescence in Myocardial Infarction
  NCT07693712 · TERMINATED · funding business
  “Staffing challenges and subsequent withdrawal of funding.”
• The Effect of Continued Mechanical Ventilation on the Occurrence of Myocardial Ischemia
  NCT05417217 · TERMINATED · logistics pi
  “After the passing of the principal investigator, the clinical trial could not be continued.”
• Dapagliflozin Effect on Cardiovascular Outcomes in Haemodialysis for End Stage Renal Disease
  NCT04764097 · WITHDRAWN · funding business
  “Lack of funding and similar competing study being conducted in Europe.”
• A 3D Hydrogel Model to Assess Endothelial Cell-macrophage Interactions in Simulated Microgravity (OR-DRPD-SRI2019)
  NCT04028752 · WITHDRAWN · funding business
  “Grant ended”
• In Vivo Glycocalyx as Predictor of Complications After Cardiac Surgery
  NCT04643535 · TERMINATED · regulatory
  “The period of authorization for effective inclusion has ended at 130 inclusions out of a theoretical 600.”
• Urica Cor Intervention (URICORI) Trial
  NCT04459936 · WITHDRAWN · logistics pi
  “The study has been terminated due to inclusion difficulties during the worldwide Covid-19 pandemic.”
• Closed-loop Control Mean Arterial Pressure In Intensive Care Patients
  NCT04357197 · WITHDRAWN · other
  “We did not want to start a case series as we already finished a RCT...SO this study is now outdated”
• Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet Prolapse
  NCT02829749 · WITHDRAWN · funding business
  “Because of dynamics in the field of minimal invasive mitral repair and the development of newer devices”
• TIME ASPIRIN: Chronotherapy With Aspirin for Reduction of Cardiovascular Disease
  NCT04132791 · TERMINATED · slow accrual
  “stopped prematurely due to too low inclusion rate”
• Management of Device Detected AT and Impact of Device Treatment Algorithms on Atrial Fibrillation
  NCT04172883 · TERMINATED · logistics pi
  “Sponsors decision to terminate the study based on the current Covid situation which is preventing completion of study milestone.”
• South Asian Low-sodium Trial
  NCT05136911 · TERMINATED · logistics pi
  “The recruitment was stopped due to province-wide lockdown secondary to COVID-19. Blood pressure screenings were conducted in community centres and due to province wide lockdown, further screenings could not be continued.”
• Increasing Caregiver and Patient Engagement Through PHR Use
  NCT03659565 · TERMINATED · slow accrual
  “Poor accrual due to Covid-19 restrictions”
• The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
  NCT04777383 · TERMINATED · logistics pi
  “The study was terminated prematurely due to insufficient operational resources to continue trial conduct and completion. The decision was unrelated to safety concerns or study outcomes.”
• Effects of Nitric Oxide on the Endothelium During Hemolysis.
  NCT03748082 · WITHDRAWN · funding business
  “Lack of funding”
• The Interrogation of the Cardiomyopathy of Chronic Kidney Disease With advancEd caRdiac Imaging
  NCT03704701 · TERMINATED · logistics pi
  “COVID-19 pandemic; pre-pandemic recruitment sufficient for scientific validity”
• Accessing Mobility Using Wearable Sensors
  NCT04306588 · WITHDRAWN · logistics pi
  “The PI moved to another institution”
• Peru Longitudinal Study
  NCT03742219 · TERMINATED · slow accrual
  “Low level of returning participants year by year.”
• IRIS-BVS AMI Registry
  NCT02699671 · TERMINATED · safety
  “current BVS safety issue”
• For Her Heart's Sake STEP Project: A Clinical Trial
  NCT02411188 · WITHDRAWN · slow accrual
  “recruitment issues; changed protocol to prospective cohort study”
• Remote Ischaemic Preconditioning to Prevent Dialysis Induced Cardiac Injury
  NCT02630355 · TERMINATED · other
  “The study was terminated prematurely after ad-interim analysis for the primary outcome.”
• CoolLoop Paroxysmal Atrial Fibrillation
  NCT02553239 · TERMINATED · slow accrual
  “insufficient patient recruitment”
• A Study of Evacetrapib in High-Risk Vascular Disease
  NCT01687998 · TERMINATED · futility
  “Study termination due to insufficient efficacy.”
• Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
  NCT00889876 · TERMINATED · funding business
  “hard to recruite, no funding”
• Therapy Study of Automated Protocolized vs. Physician-Directed Non-Protocolized Weaning
  NCT00606788 · SUSPENDED · other
  “Interim analysis indicated that sample size of study patients had to be highly increased to obtain significant outcomes.”
• Genomic Dissection of a QTL Affecting the Lipid Profile
  NCT00064688 · WITHDRAWN · funding business
  “This protocol was created to support work as part of an NIH-funded study.”
• Magnetic Resonance Imaging-Portfolio Diet Study #7
  NCT02078635 · WITHDRAWN · other
  “Study was amalgamated with another study to include exercise as another intervention.”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.