Acute Lymphoblastic Leukemia

Why trials studying Acute Lymphoblastic Leukemia stopped, in this sample of ClinicalTrials.gov.

17 stopped trials with a clear reason; 94% ended for non-scientific reasons.

Trials

• Continuous Ambulatory Monitoring to Predict Elevated Risk of Infection in Children With Lymphoblastic Leukemia Undergoing Induction Chemotherapy (CAMPER-ALL)
  NCT04322084 · WITHDRAWN · staffing, sites or logistics
  “The study was activated at the onset of the COVID pandemic. At that time voluntary, non-therapeutic research was placed on hold. Now the technology has evolved and have elected to forego this protocol.”
• Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia
  NCT05410574 · TERMINATED · staffing, sites or logistics
  “Insufficient staff”
• CD19.CAR-multiVSTs for Patients With CD19+ B-ALL or NHL Undergoing Related Allogeneic HSCT (CARMA)
  NCT03768310 · WITHDRAWN · funding or business
  “We decided to move on to another product and as a result will not be moving forward with this study.”
• Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL)
  NCT04225676 · TERMINATED · slow enrollment
  “Terminated due to slow enrollment”
• Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation
  NCT03856216 · TERMINATED · slow enrollment
  “\<75% participation”
• Allogeneic Donor Lymphocyte Infusions Combined With Blinatumomab
  NCT03982992 · WITHDRAWN · slow enrollment
  “Lack of potential study subjects due to a change of standard of care treatment outside of clinical trials.”
• REALIB-LLA-2017: Idelalisib in Patients With Acute Lymphoblastic Leukemia
  NCT03742323 · TERMINATED · slow enrollment
  “Because of low recruitment”
• Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia
  NCT03195010 · TERMINATED · slow enrollment
  “Terminated because of slow recruitment and lack of funding support”
• Intravenous Zoledronic Acid for the Treatment of Osteoporosis and Osteonecrosis in Children With Leukemia: A Pilot Study
  NCT02632903 · WITHDRAWN · funding or business
  “While the clinical need for and the scientific merit remain valid, this regulated drug trial was not feasible logistically due to limited funds.”
• Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant
  NCT02065869 · TERMINATED · funding or business
  “Sponsor decision”
• Metformin and Transient Hyperglycemia
  NCT01486043 · TERMINATED · slow enrollment
  “The research project was terminated due to lower than projected patient recruitment within the period of time allowed for the study.”
• Haploidentical Stem Cell Transplantation With CD3/CD19 Depletion and Reduced Intensity Conditioning in Patients With Acute Leukemia
  NCT00961142 · TERMINATED · slow enrollment
  “slow recruitment”
• Nilotinib With Chemotherapy for the Treatment of Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
  NCT00905398 · TERMINATED · slow enrollment
  “The study was terminated due to excessive toxicity and low compliance to the protocol scheme.”
• Study of Immune Response Modifier in the Treatment of Hematologic Malignancies
  NCT00276159 · TERMINATED · drug or device supply
  “Drug was not available.”
• Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
  NCT00187005 · TERMINATED · safety
  “Toxicity”
• Treatment of Childhood Acute Lymphoblastic Leukemia
  NCT00165087 · TERMINATED · regulatory or ethics
  “Terminated by IRB for continuing review”
• Cardiometabolic Status in Childhood Acute Lymphoblastic Leukemia
  NCT01688752 · WITHDRAWN · funding or business
  “Funding unavailable”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.